Recombinant Human UBE2V2/DDVIT1 Protein (His Tag)

SKU: PKSH033191

Size: 50μg

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: UBE2V2;DDVIT1

Target Synonym: DDVit 1;EDAF-1;EDPF-1;Enterocyte Differentiation-Associated Factor 1;Enterocyte Differentiation-Promoting Factor 1;MMS2;MMS2 Homolog;UBE2V2;UEV2;Ubiquitin-Conjugating Enzyme E2 Variant 2;Vitamin D3-Inducible Protein

Research Areas: Cell biology;epigenetics and nuclear signal

Conjugation:

Target Species: Human

Expression Host: E.coli

Application:

Fusion tag: N-His

UNIProt ID: Q15819

Accession: Q15819

Background: Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2) is an enzyme that belongs to the ubiquitin-conjugating enzyme family. UBE2V2 can be detected in the placenta, colon, liver, and skin. It forms a heterodimer with UBE2N. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains and which leads to protein degradation by the proteasome. UBE2V2 mediates transcriptional activation of target genes. It plays a role in the control of progress through the cell cycle and differentiation. It also plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.

Concentration:

Activity: Not validated for activity

Sequence: Met 1-Asn145

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 50mm HEPES,150mM NaCl, pH 7.0.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 18.5 kDa

ObservedMW: 18 kDa