Recombinant Human UBE2B/HR6B Protein (His Tag)

SKU: PKSH033180

Size: 50μg

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: UBE2B;HR6B

Target Synonym: HR6B;RAD6 Homolog B;RAD6B;UBE2B;Ubiquitin Carrier Protein B;Ubiquitin-Conjugating Enzyme E2 B;Ubiquitin-Conjugating Enzyme E2-17 kDa;Ubiquitin-Protein Ligase B;hHR6B

Research Areas: Cell biology;Cancer;epigenetics and nuclear signal;metabolism

Conjugation:

Target Species: Human

Expression Host: HEK293 Cells

Application:

Fusion tag: C-His

UNIProt ID: P63146

Accession: P63146

Background: Ubiquitin-Conjugating Enzyme E2 B (UBE2B) is a member of the ubiquitin-conjugating enzyme family. UBE2B accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. It is shown that UBE2B interacts with RAD18; UBR2; and WAC. UBE2B is required for post-replicative DNA damage repair. Additional; UBE2B plays a role in sepsis-induced muscle protein proteolysis and cancer-induced cachexia.

Concentration:

Activity: Not validated for activity

Sequence: Met 1-Ser152

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 18.3 kDa

ObservedMW: 17 kDa