Recombinant Human TSTA3/SDR4E1 Protein (His Tag)

SKU: PKSH032483

Size: 50μg

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: TSTA3;SDR4E1

Target Synonym: 5-Epimerase-4-Reductase;GDP-4-Keto-6-Deoxy-D-Mannose-3;GDP-L-Fucose Synthase;Protein FX;Red Cell NADP(H)-Binding Protein;SDR4E1;Short-Chain Dehydrogenase/Reductase Family 4E Member 1;TSTA3

Research Areas: Signal Transduction;metabolism;

Conjugation:

Target Species: Human

Expression Host: E.coli

Application:

Fusion tag: C-His

UNIProt ID: Q13630

Accession: Q13630

Background: GDP-L-Fucose Synthase is a NADP(H)-binding protein. It catalyzes the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-dexoymannose to GDP-L-fucose. GDP-L-Fucose is the substrate of several fucosyltransferase, involving the expression of mamy glycoconjugates, including blood group ABH antigens and development adhesion antigens. Mutations in the TSTA3 gene may cause leukocyte adhesion deficiency type II.

Concentration:

Activity: Not validated for activity

Sequence: Met 1-Lys321

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 37.0 kDa

ObservedMW: 40 kDa