Recombinant Human SELE Protein(His Tag)

SKU: PDMH100284

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:SELE

Target Synonym:CD26E;CD62 antigen-like family member E;CD62E;E selectin;E-selectin;ELAM;ELAM-1;ELAM1;Endothelial adhesion molecule 1;Endothelial leukocyte adhesion molecule 1;ESEL;LECAM2;Leukocyte-endothelial cell adhesion molecule 2;LYAM2;Sele;Selectin E

Research Areas:Cancer;Cardiovascular;Immunology;Stem Cells

Conjugation:

Target Species:Human

Expression Host:stable cell line

Application:

Fusion tag:C-His

UNIProt ID:P16581

Accession:P16581

Background:The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin-and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.

Concentration:

Activity:Not validated for activity

Sequence:Met1-Pro556

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW:61 kDa

ObservedMW:80-100 kDa