Recombinant Human S100A8 Protein (His Tag)

SKU: PKSH033008

Size: 50μg

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: S100A8

Target Synonym: 60B8AG;CAGA;CFAG;CGLA;CP-10;Calgranulin-A;Cystic fibrosis antigen;L1Ag;Leukocyte L1 complex light chain;MA387;MIF;MRP-8;MRP8;NIF;P8;Protein S100-A8;S100A8

Research Areas: Cell biology;Neuroscience;Cancer;epigenetics and nuclear signal;immunology

Conjugation:

Target Species: Human

Expression Host: E.coli

Application:

Fusion tag: C-His

UNIProt ID: P05109

Accession: P05109

Background: Protein S100-A8 (also MRP8 and calgranulin A) is a calcium- and zinc-binding protein.It plays a prominent role in the regulation of inflammatory processes and immune response. S100A8 can induce neutrophil chemotaxis and adhesion. Its role as an oxidant scavenger has a protective role in preventing exaggerated tissue damage by scavenging oxidants. It can act as a potent amplifier of inflammation in autoimmunity as well as in cancer development and tumor spread.

Concentration:

Activity: Not validated for activity

Sequence: Met 1-Glu93

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 8% Sucrose, 150mM NaCl, 20% Glycerol, 2mM EDTA, 0.05% Tween 80, pH8.5

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 11.7 kDa

ObservedMW: 13 kDa