Recombinant Human RGMA Protein (E.coli, His Tag)

SKU: PKSH033343

Size: 50μg

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Cytokines

Abbreviation: RGMA

Target Synonym: RGM;RGM domain family member A;Repulsive guidance molecule A

Research Areas: Neuroscience;Stem cells

Conjugation:

Target Species: Human

Expression Host: E.coli

Application:

Fusion tag: N-His

UNIProt ID:

Accession: AAI51133.1

Background: Repulsive guidance molecule A（RGMA） is a cell membrane protein and belongs to the repulsive guidance molecule (RGM) family. It interacts with NEO1; BMP2 and BMP4. RGMA is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that forms after a brain injury. This protein may also function as a tumor suppressor in some cancers.

Concentration:

Activity: Not validated for activity

Sequence: Pro169-Gly422

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 20mM PB, 10% Trehalose, 50% Glycerol, 1mM DTT, 0.05% Tween 80, pH 7.8.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 29.8 kDa

ObservedMW: 30 kDa