Recombinant Human PTHrP protein

SKU: CD01027

Size:10 ug

Background:Parathyroid Hormone-like related Protein (PTHrP) is a member of the Parathyroid hormone family that is expressed in the mammary gland. It is known as a potent inhibitor of chondrocyte maturation. PTHrP is expressed by periarticular perichondrial cells and exerts its biological activity on PP-R expressing cells. During endochondral bone development PTHrP plays a major role in suppressing the onset of hypertrophic differentiation. PTHrP plays a central role in regulating the extracellular concentrations of calcium and phosphorous and it is responsible for most cases of humoral hypercalcemia of malignancy.

Research_area:Others

Purity:> 98 % by SDS-PAGE and HPLC analyses.

Source:Escherichia coli.

Full product name:Recombinant Human Parathyroid Hormone-related Protein

Biological activity:Data not available.

Synonyms:PTHLH,BDE2, HHM, PLP, PTHR, PTHRP,PTHrP, Human

Endotoxin:Less than 0.1 EU/μg of rHuPTHrP as determined by LAL method.

Storage:-20ºC

Sequence:AVSEHQLLHD KGKSIQDLRR RFFLHHLIAE IHTAEIRATS EVSPNSKPSP NTKNHPVRFG SDDEGRYLTQ ETNKVETYKE QPLKTP

uniprot accession:P12272

Molecular weight:Approximately 9.9 kDa, a single non-glycosylated polypeptide chain containing 86 amino acids.

Formulation:

Reconstitution:Lyophilized from a .2 μm filtered concentrated solution in 1 mM PB, pH 6., 3 mM NaCl.