Recombinant Human PPM1G/PP2C-gamma Protein (His Tag)

SKU: PKSH032970

Size: 50μg

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: PPM1G;PP2C-gamma

Target Synonym: PP2C-Gamma;PP2CG;PP2CGAMMA;PPM1G;Protein Phosphatase 1C;Protein Phosphatase 1G;Protein Phosphatase 2C Isoform Gamma;Protein Phosphatase Magnesium-Dependent 1 Gamma

Research Areas: Signal Transduction;Cell biology;epigenetics and nuclear signal;

Conjugation:

Target Species: Human

Expression Host: E.coli

Application:

Fusion tag: C-His

UNIProt ID: O15355

Accession: O15355

Background: Protein Phosphatase 1G (PP1MG) is a cytoplasmic protein that belongs to the PP2C family. PPM1G is widely expressed; it is abundant in testis; skeletal muscle; and heart. PPM1G is a negative regulator of cell stress response pathways. PPM1G is responsible for the dephosphorylation of Pre-mRNA splicing factors; an important factor for the formation of functional spliceosome. PPM1G also plays a role in regulating cell cycle progression.

Concentration:

Activity: Not validated for activity

Sequence: Met317-Asp546

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 25mM Tris-HCl, 1mM DTT, 1mM EDTA, 2mM β-ME, 20% Glycerol, pH 7.5.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 26.2 kDa

ObservedMW: 30 kDa