Recombinant Human PPIase/PPIL1 Protein (His Tag)

SKU: PKSH033304

Size: 50μg

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: PPIase;PPIL1

Target Synonym: CGI;UNQ;PRO;PPIL;CYPL;PPIase FKBP;Rotamase PPIL;FK506-Binding Protein;Peptidyl-Prolyl Cis-Trans Isomerase FKBP;Peptidyl-Prolyl Cis-Trans Isomerase-Like;PPIL1;CGI-124;CYPL1;PPIase;hCyPX;23 kDa FK506-Binding Protein;23 kDa FKBP;FK506-Binding Protein 7;FKBP23;FKBP-23;FKBP7;FKBP-7;Peptidyl-Prolyl Cis-Trans Isomerase FKBP7;Peptidyl-Prolyl Cis-Trans Isomerase-Like 1;PPIase FKBP7;Rotamase;Rotamase PPIL1;UNQ2425;PRO4984;peptidylprolyl isomerase like 1

Research Areas: Signal Transduction;epigenetics and nuclear signal;immunology;

Conjugation:

Target Species: Human

Expression Host: E.coli

Application:

Fusion tag: N-His

UNIProt ID: Q9Y3C6

Accession: Q9Y3C6

Background: Peptidyl-Prolyl Cis-Trans Isomerase-Like 1 (PPIase) belongs to the cyclophilin-type PPIase family. PPIases can accelerate the folding of proteins and catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIase is a ubiquitous protein and has highly expression in heart ;skeletal and muscle. PPIase contains a PPIase cyclophilin-type domain and four Cyclosporin A binding regions. PPIase might play an important role in proliferation of cancer cells through modulation of phosphorylation of stathmin. It is suggested that PPIase can act as as a novel molecular target for colon-cancer therapy.

Concentration:

Activity: Not validated for activity

Sequence: Met 1-Gly166

Purity: > 90 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, pH 8.0.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 20.4 kDa

ObservedMW: 19 kDa