Recombinant Human PODXL Protein(GST Tag)

SKU: PDEH100646

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:PODXL

Target Synonym:Podocalyxin-like protein;PODXL;Gp200;PC;PCLP;PCLP-1;GCTM-2 antigen;GCTM;Gp200MGC138240;PCLP1;PCpodocalyxin;Podocalyxin;podocalyxin-like;PCLPGCTM-2 antigen;POD XL;Podocalyxin-like protein 1;Gp200;PCLP;PCLP 1;PCLP1;Podocalyxin;podocalyxin like;Podocalyxin like protein 1;PODXL;RCC marker;Renal Cell Carcinoma marker;TRA 1 81;TRA-1-60;GCTM 2 antigen;TRA 1 60

Research Areas:Stem Cells;Developmental Biology;Signal Transduction;Cancer;Cardiovascular

Conjugation:

Target Species:Human

Expression Host:E.coli

Application:

Fusion tag:N-GST

UNIProt ID:O00592

Accession:O00592

Background:Podocalyxin-like protein (PODXL) is a member of CD34 family proteins. It is the protein that carries many post-translational epitopes responsible for various pluripotent surface markers including TRA-1-60, TRA-1-81, GCTM2, GP200, and mAb84.Podocalyxin-like 1 (PODXL) was reported to be closely associated with the development of various cancers.KLF4/PODXL signaling pathway assumes an irreplaceable role in tumorigenesis, invasion and metastasis of human GC and PODXL serves as an independent prognostic indicator for GC patients. PODXL may be a novel, non-invasive diagnostic biomarker for the detection of pancreatic cancer.

Concentration:

Activity:Not validated for activity

Sequence:Ser23-Leu428

Purity:> 80% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis

Endotoxin:< 10 EU/mg of the protein as determined by the LAL method

Calculated MW:70.6 kDa

ObservedMW:78 kDa