Recombinant Human Placental Alkaline Phosphatase 1/ALPP Protein (His Tag)

SKU: PKSH032058

Size: 50μg

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: ALPP

Target Synonym: ALPP and PLAP;Alkaline phosphatase;Alkaline phosphatase Regan isozyme;Placental alkaline phosphatase 1;placental type

Research Areas: Tags & Cell Markers;Cell biology;Cancer

Conjugation:

Target Species: Human

Expression Host: HEK293 Cells

Application:

Fusion tag: C-His

UNIProt ID: P05187

Accession: P05187

Background: ALPP is a membrane protein and exits as a homodimer. ALPP is expressed only in normal term placenta, endocervix and fallopian tube and also in ovarian and proximal gastrointestinal tumors. It has been shown to play a role in a number of processes including cell signaling, long-term potentiation, and cell adhesion, however, the best known and most commonly studied role is implicated in Alzheimer's research.

Concentration:

Activity: Not validated for activity

Sequence: Ile23-Asp506

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 0.2mM CaCl₂, 10% Glycerol, pH 7.5.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 53.7 kDa

ObservedMW: 60-85 kDa