Recombinant Human PGD Protein (Human Cells, His Tag)

SKU: PKSH033424

Size: 50μg

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: PGD

Target Synonym: 6-phosphogluconate dehydrogenase;6PGD;Decarboxylating;PGD;PGDH

Research Areas: Signal Transduction;metabolism;

Conjugation:

Target Species: Human

Expression Host: HEK293 Cells

Application:

Fusion tag: C-His

UNIProt ID: P52209

Accession: P52209

Background: 6-phosphogluconate dehydrogenase(PGD) is a cytoplasm-located protein; and belongs to the 6-phosphogluconate dehydrogenase family. 6PGD is the second dehydrogenase in the pentose phosphate shunt. It catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO2; with concomitant reduction of NADP to NADPH. Mutations within the gene coding this enzyme result in 6-phosphogluconate dehydrogenase deficiency; an autosomal hereditary disease effecting the red blood cells.

Concentration:

Activity: Not validated for activity

Sequence: Met 1-Ala483

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 54.2 kDa

ObservedMW: 58 kDa