Recombinant Human PDCD4 protein (His Tag)

SKU: PDEH100700

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:PDCD4

Target Synonym:Death up-regulated gene protein;Dug;H731;MGC33046;MGC33047;Ma3;Neoplastic transformation inhibitor;Neoplastic transformation inhibitor protein;Nuclear antigen H731;Nuclear antigen H731 like;Nuclear antigen H731 like protein;Nuclear antigen H731-like;PDCD

Research Areas:Cell biology;Cancer;epigenetics and nuclear signal

Conjugation:

Target Species:Human

Expression Host:E.coli

Application:Immunogen

Fusion tag:N-His

UNIProt ID:Q53EL6

Accession:Q53EL6

Background:Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation.

Concentration:

Activity:Not validated for activity

Sequence:Met1-Asn325

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from sterile PBS, pH 7.4.
Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 10 EU/mg of the protein as determined by the LAL method.

Calculated MW:36.9 kDa

ObservedMW:41-43 kDa