Recombinant Human MICB Protein(Fc Tag)

SKU: PDMH100236

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:MICB

Target Synonym:MHC class I chain-related protein A;MHC class I chain-related protein B;MHC class I polypeptide related sequence A;MHC class I polypeptide related sequence B;MHC class I polypeptide-related sequence A;MIC-A;micA;MICA_HUMAN;MICB

Research Areas:Immunology

Conjugation:

Target Species:Human

Expression Host:Mammalian

Application:

Fusion tag:C-Fc

UNIProt ID:Q29980

Accession:Q29980

Background:This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules, however, it does not associate with an beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants.

Concentration:

Activity:Not validated for activity

Sequence:Ala23-Gly298

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW:55.2 kDa

ObservedMW:60-80 kDa