Recombinant Human LAMTOR3/MP1 Protein (His Tag)

SKU: PKSH032742

Size: 50μg

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: LAMTOR3;MP1

Target Synonym: LAMTOR3;Late Endosomal/Lysosomal Adaptor and MAPK and MTOR Activator 3;MAP2K1IP;MEK-Binding Partner 1;Mitogen-Activated Protein Kinase Kinase 1-Interacting Protein 1;Mitogen-Activated Protein Kinase Scaffold Protein 1;Mp1;Ragulator Complex Protein LAMTOR3

Research Areas: Signal Transduction;

Conjugation:

Target Species: Human

Expression Host: E.coli

Application:

Fusion tag: N-His

UNIProt ID: Q9UHA4

Accession: Q9UHA4

Background: Mitogen-Activated Protein Kinase Scaffold Protein 1 (MAPKSP1) was identified as an interacting protein that belongs to the LAMTOR3 family. MAPKSP1 restricted to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. MAPKSP1 interacts with MAP2K1/MEK1 and MAPK2 and enhances the activation of MAPK2, and thus is thought to function as an adaptor to enhance the efficiency of the MAP kinase cascade.

Concentration:

Activity: Not validated for activity

Sequence: Met 1-Val124

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 5mM DTT, 30% Glycerol, pH 8.0.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 15.8 kDa

ObservedMW: 15 kDa