Recombinant Human IL-1α Protein

SKU: PDMH100025

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:IL-1α

Target Synonym:IL1F;IL1A;IL-1A;IL1;IL1-ALPHA;IL1F1;BAF;FAF;Hematopoietin 1;Hematopoietin-1;IL 1 alpha;IL 1A;IL1 ALPHA;IL-1 alpha;IL1-A;Interleukin 1 alpha;Interleukin1 alpha;Interleukin-1 alpha;LAF;LEM;Preinterleukin 1 alpha;Pro interleukin 1 alpha;Pro-Interleukin-1-Alpha

Research Areas:Cancer;Cardiovascular;Immunology;

Conjugation:

Target Species:Human

Expression Host:HEK293 Cells

Application:

Fusion tag:C-His

UNIProt ID:P01583

Accession:P01583

Background:Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.

Concentration:

Activity:Not validated for activity

Sequence:Met1-Ala271

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from sterile PBS, pH 7.4., 5% trehalose, 5% mannitol, 0.01% Tween 80.
Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW:30.6 kDa

ObservedMW:35 kDa