Recombinant Human DYNLL1 Protein (His Tag)

SKU: PKSH032338

Size: 50μg

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: DYNLL1

Target Synonym: 8 kDa Dynein Light Chain;DLC1;DLC8;DNCL1;DNCLC1;DYNLL1;Dynein Light Chain 1 Cytoplasmic;Dynein Light Chain LC8-Type 1;HDLC1 ;PIN;Protein Inhibitor of Neuronal Nitric Oxide Synthase

Research Areas: Signal Transduction;Cell biology;Neuroscience;Cancer;epigenetics and nuclear signal;metabolism;

Conjugation:

Target Species: Human

Expression Host: E.coli

Application:

Fusion tag: N-His

UNIProt ID: P63167

Accession: P63167

Background: Human Dynein Cytoplasmic Light Chain 1 (DYNLL1) has been identified as a protein that interacts with NOS1, leading to NOS1 inhibition. NOS1 dimer is destabilized after binding DYNLL1 a conformation necessary activity, and it regulate numerous biologic processes throughits effects on nitric oxide synthase activity. DYNLL1 is widely expressed, with higher expression in testis and moderate expression in brain.

Concentration:

Activity: Not validated for activity

Sequence: Met 1-Gly89

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM Histidine-HCl, 10% Trehalose, 0.05% Tween 80, pH6.0.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 12.5 kDa

ObservedMW: 14 kDa