Recombinant Human CD48/SLAMF2 Protein(Fc Tag)

SKU: PDMH100309

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Immune Checkpoint Proteins

Abbreviation:CD48/SLAMF2

Target Synonym:MEM;hCD;mCD;BCM;sgp;TCT;Leukocyte antigen MEM;B-lymphocyte activation marker BLAST;HM48;SLAMF;CD48;BCM1;BLAST;BLAST1;MEM-102;SLAMF2;hCD48;mCD48;BCM1 surface antigen;BLAST-1;B-lymphocyte activation marker BLAST-1;CD48 antigen;HM48-1;Leukocyte antigen MEM-102;MRC OX-45 surface antigen;sgp-60;TCT.1; BCM1; Sgp-60; SLAMF2;Antigen CD48;B cell membrane protein;B lymphocyte activation marker BLAST 1;B-cell activation marker;BCM 1 surface antigen;BLAST 1;CD 48;CD48 antigen (B cell membrane protein);CD48 molecule;CD48 protein;Leucocyte antigen MEM 102;MEM 102;MEM102;Signaling lymphocytic activation molecule 2;SLAM family member 2;SLAMF 2

Research Areas:Immunology

Conjugation:

Target Species:Human

Expression Host:Mammalian

Application:

Fusion tag:C-Fc

UNIProt ID:P09326

Accession:P09326

Background:Cluster of Differentiation 48 (CD48) , also known as SLAMF2 , BCM-1 and BLAST-1 , is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 protein performs biological functions in a variety processes including adhesion , pathogen recognition , cellular activation , and cytokine regulation , and emerges as a critical effector molecule in immune responses.

Concentration:

Activity:Not validated for activity

Sequence:Gln27-Ser220

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW:46.2 kDa

ObservedMW:60 kDa