Recombinant Human BCL2 Protein(Sumo Tag)

SKU: PDEH101115

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:BCL2

Target Synonym:B-cell lymphoma 2;Apoptosis regulator Bcl-2;PPP1R50

Research Areas:Cancer;Cell Biology;Signal Transduction

Conjugation:

Target Species:human

Expression Host:E.coli

Application:

Fusion tag:N-Sumo

UNIProt ID:P10415

Accession:P10415

Background:This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.

Concentration:

Activity:Not validated for activity

Sequence:Met1-Asp211

Purity:> 95% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis

Endotoxin:< 10 EU/mg of the protein as determined by the LAL method

Calculated MW:36.1 kDa

ObservedMW:38 kDa