Recombinant Human ALDH1A1/ALDC Protein (His Tag)

SKU: PKSH032052

Size: 50μg

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: ALDH1A1;ALDC

Target Synonym: ALDC;ALDH-E1;ALDH1;ALDH11;ALDH1A1;ALHDII;Aldehyde Dehydrogenase Cytosolic;Aldehyde Dehydrogenase Family 1 Member A1;HEL-9;HEL-S-53e;HEL12;PUMB1;PUMB10;RALDH 1;RALDH1;RalDH1;Retinal Dehydrogenase 1

Research Areas: Neuroscience;Cancer;Stem cells

Conjugation:

Target Species: Human

Expression Host: E.coli

Application:

Fusion tag: N-His

UNIProt ID: P00352

Accession: P00352

Background: Aldehyde Dehydrogenase Family 1 Member A1 (ALDH1A1) is a cytoplasmic enzyme that belongs to the Aldehyde Dehydrogenase family. ALDH1A1 is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties and subcellular localizations. ALDH1A1 is the main cytosolic isoform, which has a lower affinity for aldehydes than the mitochondrial enzyme. ALDH1A1 binds free retinal and cellular retinol-binding protein-bound retinal. It can convert/oxidize retinaldehyde to retinoic acid.

Concentration:

Activity: Not validated for activity

Sequence: Met 1-Ser501

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 20% Glycerol, 1mM DTT, pH 8.0.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 57.0 kDa

ObservedMW: 60 kDa