Recombinant Human ADGRE5 Protein(His Tag)

SKU: PDMH100241

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:ADGRE5

Target Synonym:ADGRE5;Adhesion G protein-coupled receptor E5;CD 97;CD_antigen=CD97;CD97;CD97 antigen;CD97 antigen subunit beta;CD97 molecule;CD97;Leukocyte antigen CD97;Seven span transmembrane protein;Seven transmembrane helix receptor;Seven transmembrane heterodimeric receptor associated with inflammation;TM7LN 1;TM7LN1

Research Areas:Cancer;Immunology;Neuroscience;Signal Transduction;Stem Cells

Conjugation:

Target Species:Human

Expression Host:Mammalian

Application:

Fusion tag:C-His

UNIProt ID:P48960

Accession:P48960

Background:This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with an 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with an other EGF-TM7 genes on the short arm of chromosome 19.

Concentration:

Activity:Not validated for activity

Sequence:Gln21-Leu530

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW:55.9 kDa

ObservedMW:80-100 kDa