Recombinant HNF-4α Monoclonal Antibody

SKU: AN300652L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:HNF-4α

Target Synonym:HNF;FRTS;HNF4A;FRTS4;HNF4;HNF4a7;HNF4a8;HNF4a9;HNF4alpha;MODY;MODY1;NR2A1;NR2A21;TCF;TCF14;FLJ39654;hepatic nuclear factor;Hepatic nuclear factor 4 alpha;Hepatocyte nuclear factor 4;Hepatocyte nuclear factor 4 alpha;Hepatocyte nuclear factor 4-alpha;HNF 4;HNF 4 alpha;HNF-4-alpha;HNF4alpha10/11/12;MODY 1;Nuclear receptor subfamily 2 group A member 1;OTTHUMP00000031060;OTTHUMP00000031062;TCF 14;TCF-14;Tcf4;Transcription factor 14;Transcription factor HNF 4;Transcription factor HNF4;Transcription factor HNF-4;HNF4α

Research Areas:Cardiovascular;Signal Transduction;Epigenetics and Nuclear Signaling;Developmental Biology;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:9F2

UNIProt ID:P41235

Accession:

Background:The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human HNF-4α protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000

Calculated MW:53 kDa

ObservedMW:53 kDa