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GeneBio Systems

Recombinant Histone H4 (Acetyl Lys12) Monoclonal Antibody

Recombinant Histone H4 (Acetyl Lys12) Monoclonal Antibody

AN301411L

$512.44 CAD
$512.44 CAD
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Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies;Acetyl/Phospho/Methyl Antibodies

Abbreviation:Histone H4 (Acetyl Lys12)

Target Synonym:H4F;methyl histone H;methylated histone H;HIST2H;HIST1H;HISTH4H;histone H;HIST2H4B;H4/o;histone H4;HIST1H4A;FO108;H4/p;HIST1H4;Hist4h4;HISTH4H4;methyl histone H4;methylated histone H4;H4/A;H4FA;H4/I;H4FI;HIST1H4B;H4/G;H4FG;HIST1H4C;H4/B;H4FB;HIST1H4D;H4/J;H4FJ;HIST1H4E;H4/C;H4FC;HIST1H4F;H4/H;H4FH;HIST1H4H;H4/M;H4FM;HIST1H4I;H4/E;H4FE;H4/D;H4FD;HIST1H4K;H4/K;H4FK;HIST1H4L;H4/N;H4F2;H4FN;HIST2H4;HIST2H4A;H4;H4C1;H4C2;H4C3;H4C4;H4C5;H4C6;H4C8;H4C9;H4C11;H4C12;H4C13;H4C14;H4C15;H4-16;A;I;H4B;H4J;H4H;H4M;H4E;HIST1H4J;H4D;H4C;H4/p;histone H4;HIST1H4B H4/I

Research Areas:Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A106

UNIProt ID:P62805

Accession:

Background:Histone post-translational modifications (PTMs), known as the “histone code”, are key mechanisms of epigenetics that modulate chromatin structures. The PTMs on histone including acetylation, methylation, phosphorylation, and novel acylations directly affect the accessibility of chromatin to transcription factors and other epigenetic regulators, altering genome stability and gene transcription. Histone acetylation, tightly controlled by the opposing action of histone acetyltransferases (HATs) and histone deacetylases (HDACs), occurs primarily at lysine residues on the N-terminal tails of histones H2A (Lys5, 9, and 15), H2B (Lys5, 12, 15, 16, and 20), H3 (Lys4, 9, 14, 18, 23, 27, and 36), and H4 (Lys5, 8, 12, 16, and 20), and plays vital roles in the regulation of gene expression, DNA damage repair, chromatin dynamics, etc.

Concentration:1 mg/mL

Immunogen:Acetylated human histone H4 (Lys12) peptide

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:1000;IHC 1:50-1:200

Calculated MW:11 kDa

ObservedMW:11 kDa

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