Recombinant Helicobacter pylori Vacuolating cytotoxin autotransporter(vacA),partial

Recombinant Helicobacter pylori Vacuolating cytotoxin autotransporter(vacA),partial

CSB-EP669657HUS
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Size: 200ug. Other sizes are also available. Please Inquire.

In Stock: Yes

Lead time: 3-7 working days

Research Topic: Microbiology

Uniprot ID: Q48253

Gene Names: vacA

Organism: Helicobacter pylori (Campylobacter pylori)

AA Sequence: KYEKPTNVWANAIGGTSLNNGSNASLYGTSAGVDAYLNGEVEAIVGGFGSYGYSSFSNQANSLNSGANNTNFGVYSRIFANQHEFDFEAQGALGSDQSSLNFKSALLQDLNQSYHYLAYSATTRASYGYDFAFFRNALVLKPSVGVSYNHLGSTNFKSNSNQVALSNGSSSQHLFNANANVEARYYYGDTSYFYMNAGVLQEFARFGSNNAVSLNTFKVNATRNPLNTHARVMMGGELQLAKEVFLNLGVVYLHNLISNASHFASNLGMRYSF

Expression Region: 1038-1310aa

Sequence Info: Partial

Source: E.coli

Tag Info: N-terminal 6xHis-SUMO-tagged

MW: 45.7 kDa

Alternative Name(s): Cleaved into the following 2 chains: Vacuolating cytotoxin Vacuolating cytotoxin translocator

Relevance: Induces vacuolation of eukaryotic cells. Causes ulceration and gastric lesions.

Reference: "Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. Association of specific vacA types with cytotoxin production and peptic ulceration."Atherton J.C., Cao P., Peek R.M. Jr., Tummuru M.K., Blaser M.J., Cover T.L.J. Biol. Chem. 270:17771-17777(1995)

Purity: Greater than 90% as determined by SDS-PAGE.

Storage Buffer: Tris-based buffer,50% glycerol

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

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