Recombinant GOT1 Monoclonal Antibody

SKU: AN301537L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:GOT1

Target Synonym:GIG;GOT;ASTQTL;GOT1;AST1;ASTQTL1;GIG18;cAspAT;cCAT;AAT;ASAT;AspAT;serum glutamic oxaloacetic transaminase;SGOT;AST;cytoplasmic;Glut;Aspartate aminotransferase;AATC;Aspartate aminotransferase 1;Aspartate aminotransferase cytoplasmic;Aspartate aminotransferase cytosolic;cysteine aminotransferase;cysteine transaminase;cytoplasmic (cCAT);ec 2.6.1.1;GIG 18;Glutamate oxaloacetate transaminase 1;Glutamate oxaloacetate transaminase soluble;Glutamic oxaloacetic transaminase 1 soluble;GOT 1;Growth inhibiting protein 18;Transaminase A

Research Areas:Signal Transduction;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A236

UNIProt ID:P17174

Accession:

Background:Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H2S via the action of 3-mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.

Concentration:1 mg/mL

Immunogen:Recombinant human GOT1 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:1000-1:2000;IHC 1:100-1:1000

Calculated MW:46 kDa

ObservedMW:46 kDa