Recombinant Glypican 1 Monoclonal Antibody

SKU: AN301911L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:Glypican 1

Target Synonym:Secreted glypican;Glypican proteoglycan;GPC;GPC1;glypican;FLJ38078;Glypican proteoglycan 1;glypican1;Glypican-1;GPC 1;Secreted glypican-1;glypican;Glypican proteoglycan 1;glypican1;GPC 1;Secreted glypican-1

Research Areas:Neuroscience;Signal Transduction;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A627

UNIProt ID:P35052

Accession:

Background:Glypicans are a family of HSPGs that are attached to the cell membrane by a glycosyl-phosphatidylinositol anchor. Glypicans are considered to have the ability to modulate the activities of HBGFs. The expression of glypicans is regulated temporally and spatially during development, suggesting they are involved in development and morphogenesis. To date, six glypicans (Glypican 1 to Glypican 6) have been identified in mammals. Glypican 1 (GPC1) is most ubiquitously expressed in adult tissues. GPC1 promotes efficient signaling by HBGFs and plays a critical role in cell growth and differentiation. GPC1 is involved in tumorigenesis and angiogenesis, and is frequently overexpressed in several types of tumors including pancreatic carcinoma, breast cancer and glioma.

Concentration:1 mg/mL

Immunogen:Recombinant human Glypican 1 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:1000

Calculated MW:62 kDa

ObservedMW:62 kDa