Recombinant Fragile histidine triad/FHIT Monoclonal Antibody

SKU: AN300276P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies

Abbreviation:FHIT

Target Synonym:FHIT;AP3Aase;FRA3B;AP3A hydrolase;AP3A hydrolase fragile site 3p14.2;Bis 5' adenosyl triphosphatase;Bis(5' adenosyl) triphosphatase;Diadenosine 5' 5''' P1 P3 triphosphate hydrolase;Dinucleosidetriphosphatase;FRA 3B;Fragile histidine triad;Fragile histidine triad gene;Fragile histidine triad protein;Tumor suppressor protein

Research Areas:Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB;ICC/IF

Isotype:IgG

Clonality:Monoclonal

Clone NO.:14B3

UNIProt ID:P49789

Accession:

Background:This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 0, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene.

Concentration:1 mg/mL

Immunogen:Recombinant Human Fragile histidine triad / FHIT Protein

Buffer:0.2 μm filtered solution in PBS with 10% Trehalose, pH7.0

Purification method:Protein A

Dilution:WB 1:500-1:2000;ICC/IF 1:20-1:100;

Calculated MW:17 kDa

ObservedMW:20 kDa