Recombinant Estrogen Receptor α Monoclonal Antibody

SKU: AN300734L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:Estrogen Receptor α

Target Synonym:NR3A;nuclear receptor subfamily;Nuclear Receptor Subfamily 3 Group A Member;member;ESR1;ER;ESR;ESRA;ESTRR;Era;NR3A1;ER alpha;ER-Alpha;Estradiol Receptor;Estrogen Receptor;Estrogen Receptor α;group A;member 1;nuclear receptor subfamily 3;Nuclear Receptor Subfamily 3 Group A Member 1;7*/654 isoform;7*/819 2 isoform;7*/822 isoform;8*/901 isoform;8*/941 isoform;DKFZp686N23123;Estrogen nuclear receptor alpha;Estrogen receptor 1;Estrogen receptor alpha;Estrogen receptor alpha 3*;Estrogen receptor alpha delta 3*;Estrogen receptor alpha delta 4 +49 isoform;Estrogen receptor alpha E1 E2 1 2;Estrogen receptor alpha E1 N2 E2 1 2;ESR1

Research Areas:Signal Transduction;Neuroscience;Epigenetics and Nuclear Signaling;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:6H7

UNIProt ID:P03372

Accession:

Background:ESR1(estrogen receptor 1) Homo sapiens This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human Estrogen Receptor α protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000

Calculated MW:66 kDa

ObservedMW:66 kDa