Recombinant CD7 Monoclonal Antibody

SKU: AN301760L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:CD7

Target Synonym:T cell antigen CD;T cell surface antigen Leu;LEU;CD7;GP40;LEU-9;TP41;Tp40;CD7 antigen;CD7 antigen (p41);CD7 molecule;CD7_HUMAN;LEU 9;LEU9;p41 protein;T cell antigen CD7;T cell leukemia antigen;T cell surface antigen Leu 9;T-cell antigen CD7;T-cell leukemia antigen;T-cell surface antigen Leu-9;Tp 40;CD7;CD7 antigen (p41);CD7 antigen;CD7 molecule;CD7_HUMAN;GP40;LEU 9;LEU9;p41 protein;T cell antigen CD7;T cell leukemia antigen;T cell surface antigen Leu 9;T-cell antigen CD7;T-cell leukemia antigen;T-cell surface antigen Leu-9;Tp 40;Tp40;TP41

Research Areas:Immunology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;

Application:WB;IHC;IF;FCM

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A468

UNIProt ID:P09564

Accession:

Background:The CD7 antigen is a membrane-embedded glycoprotein with a molecular weight of 37-40 kDa and a member of the immunoglobulin supergene family. It plays an important role in T-cell and T-cell/B-cell interactions during early lymphoid development. CD7 is the earliest T-cell-associated molecule to appear in stem cells and prethymic stages and extends its expression all the way to the mature T cells. This molecule is also present on NK cells. In addition, the pluripotent bone marrow stem cells may express CD7. A subpopulation of AML, particularly those with monocytic or megakaryocytic differentiation, may express CD7. Lack of CD7 expression can be used for the detection of T-cell lymphoproliferative disorders, such as mycosis fungoides/Sezary syndrome and adult T-cell leukemia/lymphoma. However, normal and reactive T cells often demonstrate variable degree of CD7 loss.

Concentration:1 mg/mL

Immunogen:Recombinant human CD7 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:50;FCM 1:50-1:100

Calculated MW:25 kDa

ObservedMW:37-40 kDa