Recombinant CD47 Monoclonal Antibody

SKU: AN301936L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:CD47

Target Synonym:MER;Protein MER;Leukocyte surface antigen CD;Antigenic surface determinant protein OA;CD47;IAP;MER6;OA3;Integrin-associated protein;Leukocyte surface antigen CD47;Antigenic surface determinant protein OA3;Integrin-associated protein (IAP);Protein MER6;Antigen identified by monoclonal 1D8;CD 47;CD47 antigen;CD47 antigen (Rh-related antigen;CD47 glycoprotein;CD47 molecule;Integrin Associated Protein;Integrin associated signal transducer;integrin-associated signal transducer);MER 6;OA 3;OTTHUMP00000041152;OTTHUMP00000041153;Rh related antigen;Surface antigen identified by monoclonal 1D8

Research Areas:Immunology;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A652

UNIProt ID:Q08722

Accession:

Background:CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. CD47 plays an important role in memory formation and synaptic plasticity in the hippocampus. CD47 is a receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 interacts with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. CD47 may prevent premature elimination of red blood cells. CD47 may be involved in membrane permeability changes induced following virus infection.

Concentration:1 mg/mL

Immunogen:Recombinant human CD47 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:1000-1:2000

Calculated MW:47-52 kDa

ObservedMW:47-52 kDa