GeneBio Systems
Recombinant CD45/PTPRC Monoclonal Antibody
Recombinant CD45/PTPRC Monoclonal Antibody
SKU:AN300293P
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Size::20μL
Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Shipping:Ice bag
Exp date:12 months
Category ID_II:Primary Antibodies
Category ID_III:Recombinant Antibodies;Monoclonal Antibodies
Abbreviation:PTPRC
Target Synonym:B220;CD45;CD45R;GP180;L-CA;LCA;LY5;T200;PTPRC;CD45 antigen;CD45R0;Ly-5;protein tyrosine phosphatase;receptor type;Receptor-type tyrosine-protein phosphatase C;CD45RO;Receptor-type tyrosine-protein phosphatase CLeukocyte common antigen (L-CA);T200;c polypeptide;CD 45;homolog of;Leukocyte common antigen;loc;Lyt-4;OTTHUMP00000033813;OTTHUMP00000033816;OTTHUMP00000033817;OTTHUMP00000038574;Protein tyrosine phosphatase receptor type c polypeptide;protein tyrosine phosphatase;receptor type;C;receptor type C;T200 glycoprotein;T200 leukocyte common antigen;B220;CD45;CD45 antigen;CD45R;GP180;L-CA;LCA;Ly-5;LY5;Protein tyrosine phosphatase;receptor type;Ptprc;Receptor-type tyrosine-protein phosphatase C;T200
Research Areas:Immunology;Signal Transduction;Neuroscience;Stem Cells;Cardiovascular
Conjugation:Unconjugated
Host:Rabbit
Species reactivity:Human
Application:IHC-P
Isotype:IgG
Clonality:Monoclonal
Clone NO.:3P8
UNIProt ID:P08575
Accession:
Background:CD45, previously called LCA (leukocyte common antigen), T200, or Ly5 in mice, is member C of the class 1 (receptor‑like) protein tyrosine phosphatase family (PTPRC). It is a variably glycosylated 180-220 kDa transmembrane protein that is abundantly expressed on all nucleated cells of hematopoietic origin . Multiple splicing isoforms of exon 4 (A), 5 (B), and 6 (C) are expressed according to cell type, developmental stage and antigenic exposure . The longest form, CD45RABC (called B220 in mouse) is expressed on B lymphocytes, The shortest form, CD45R0, lacking exons 4, 5 and 6 which encode aa 34‑194, is expressed on memory cells, while intermediate sizes are expressed on other T cells.
Concentration:1 mg/mL
Immunogen:A synthetic peptide corresponding to the C-terminus of the Human CD45/PTPRC
Buffer:0.2 μm filtered solution in PBS
Purification method:Protein A
Dilution:IHC-P 1:100-1:500
Calculated MW:
ObservedMW:
