Recombinant Carbonic Anhydrase 9 Monoclonal Antibody

SKU: AN301053L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:Carbonic Anhydrase 9

Target Synonym:CA9;CAIX;MN;CA-IX;Carbonate dehydratase IX;Carbonic Anhydrase IX;Carbonic Dehydratase;P54/58N;RCC;RCC-Associated Protein G250;G250;CAH9;Carbonic anhydrase 9;Membrane antigen MN;pMW1;RCC associated protein G250;RCC-associated antigen G250;Renal cell carcinoma-associated antigen G250;CA IX

Research Areas:Cardiovascular;Signal Transduction;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:8D1

UNIProt ID:Q16790

Accession:

Background:Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human Carbonic Anhydrase 9 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:200-1000;WB 1:1000-5000

Calculated MW:49 kDa

ObservedMW:49 kDa