Recombinant C/EBP α Monoclonal Antibody

SKU: AN300671L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:C/EBP α

Target Synonym:CEBPA;C/EBP-alpha;CEBP;alpha;Apoptotic cysteine protease;Apoptotic protease Mch 5;C/EBP alpha;C/ebpalpha;CAP4;Caspase 8 precursor;CBF-A;CCAAT enhancer binding protein alpha;CCAAT/enhancer binding protein (C/EBP);CCAAT/enhancer binding protein alpha;CCAAT/enhancer-binding protein alpha;CEBP A;CEBP alpha;FADD homologous ICE/CED 3 like protease;FADD like ICE;FLICE;ICE like apoptotic protease 5;ICE8;MACH;MCH5;MORT1 associated CED 3 homolog

Research Areas:Cardiovascular;Epigenetics and Nuclear Signaling;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:2C9

UNIProt ID:P49715

Accession:

Background:This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human C/EBP α protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000;

Calculated MW:38 kDa

ObservedMW:38 kDa