Recombinant BMP-4 Monoclonal Antibody

SKU: AN301282L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:BMP-4

Target Synonym:OFC;DVR;MGC;ZGC;Bone morphogenetic protein;zbmp;MCOPS;BMP;BMP4;BMP2B;BMP2B1;MCOPS6;OFC11;ZYME;BMP 2B;BMP 4;BMP-2B;BMP-4;Bone morphogenetic protein 2B;Bone morphogenetic protein 4;MGC100779;zbmp-4;zgc:100779;DVR4;BMP-4

Research Areas:Cardiovascular;Signal Transduction;Stem Cells;Cancer;Developmental Biology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:9B8

UNIProt ID:P12644

Accession:

Background:Defects in BMP4 are the cause of microphthalmia syndromic type 6 (MCOPS6) [MIM:607932]; also known as microphthalmia and pituitary anomalies or microphthalmia with brain and digit developmental anomalies. Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues (anophthalmia). In many cases, microphthalmia/anophthalmia occurs in association with syndromes that include non-ocular abnormalities. MCOPS6 is characterized by microphthalmia/anophthalmia associated with facial, genital, skeletal, neurologic and endocrine anomalies.,Induces cartilage and bone formation. Also act in mesoderm induction, tooth development, limb formation and fracture repair.,online information:Bone morphogenetic protein 4 entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked (By similarity). Interacts with GREM2 (By similarity) and SOSTDC1. Part of a complex consisting of TWSG1 and CHRD.,tissue specificity:Expressed in the lung and lower levels seen in the kidney. Present also in normal and neoplastic prostate tissues, and prostate cancer cell lines.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human BMP-4 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:200-1:1000

Calculated MW:

ObservedMW: