Recombinant beta Catenin Monoclonal Antibody

SKU: E-AB-81445

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies

Abbreviation:beta Catenin

Target Synonym:Beta catenin;Beta-catenin;Cadherin associated protein;Catenin (cadherin associated protein);beta 1;88kDa;Catenin beta 1;Catenin beta-1;CATNB;CHBCAT;CTNB1;CTNNB;CTNNB1;DKFZp686D02253;FLJ25606;FLJ37923;OTTHUMP00000162082;OTTHUMP00000165222;OTTHUMP00000165223;OTTHUMP00000209288;OTTHUMP00000209289

Research Areas:Cancer;Cardiovascular;Neuroscience;Signal Transduction;Stem Cells

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat;Hamster

Application:WB;IHC-P

Isotype:IgG

Clonality:Rabbit Monoclonal

Clone NO.:R06-1E2

UNIProt ID:P35222

Accession:

Background:CTNNB1,also known as β-Catenin,is an evolutionarily conserved,multifunctional intracellular protein. CTNNB1 was originally identified in cell adherens junctions (Ajs) where it functions to bridge the cytoplasmic domain of cadherins to a-catenin and the actin cytoskeleton. Besides its essential role in the Ajs,CTNNB1 is also a key downstream component of the canonical Wnt pathway that plays diverse and critical roles in embryonic development and adult tissue homeostasis. Deregulation of CTNNB1 activity is associated with multiple diseases including cancers. .

Concentration:300 μg/mL

Immunogen:A synthetic peptide of human beta Catenin

Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Purification method:Affinity Purified

Dilution:WB 1:1000-1:2000;IHC 1:50-1:100

Calculated MW:86kDa

ObservedMW:86kDa