Recombinant BACE Monoclonal Antibody

SKU: AN301340L

Size::

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:BACE

Target Synonym:ASP;HSPC;KIAA;Beta-secretase;Aspartyl protease;Beta-site APP cleaving enzyme;Membrane-associated aspartic protease;Beta-site amyloid precursor protein cleaving enzyme;Memapsin;BACE1;ASP2;BACE;HSPC104;KIAA1149;Memapsin-2;Beta-secretase 1;Aspartyl protease 2;Beta-site amyloid precursor protein cleaving enzyme 1;Beta-site APP cleaving enzyme 1;Membrane-associated aspartic protease 2;Beta Secretase 1;Memapsin 2

Research Areas:Neuroscience;Cell Biology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:8A5

UNIProt ID:P56817

Accession:

Background:BACE1(beta-secretase 1) Homo sapiens This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human BACE protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:1000-1:5000

Calculated MW:56 kDa

ObservedMW:70 kDa