Recombinant Angiopoietin-2/ANG 2 Monoclonal Antibody

SKU: AN300346P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:ANGPT2

Target Synonym:angiopoitin;ANGP;Ang;ANGPT2;AGPT2;ANG2;AGPT 2;ANG 2;angiopoietin 2;Angiopoietin 2a;Angiopoietin 2B;Angiopoietin2;angiopoietin-2a;angiopoietin-2B;angiopoitin 2;ANGP2;ANGPT 2;Tie2 ligand;Tie2-ligand;Angiopoietin-2;ANG-2;Agpt2;ANG2;Angiopoietin 2a;Angiopoietin 2B;Angiopoietin2;ANGPT 2;Angpt2;Tie2 ligand

Research Areas:Cardiovascular

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB;ICC/IF;IP

Isotype:IgG

Clonality:Monoclonal

Clone NO.:6A6

UNIProt ID:O15123

Accession:

Background:Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal. Involved in the regulation of lymphangiogenesis.

Concentration:1 mg/mL

Immunogen:Recombinant Human Angiopoietin-2/ANG 2 protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:WB 1:500-1:1000;ICC/IF 1:100-1:500;IP 0.2-1 μL/mg of lysate

Calculated MW:57 kDa

ObservedMW:70 kDa