Recombinant Amyloid-β Monoclonal Antibody

SKU: AN300886L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:Amyloid-β

Target Synonym:preA;Amyloid beta A;Beta-amyloid protein;Amyloid Precursor Protein;APP A4 AD;AAA;ABETA;ABPP;AD1;APPI;CTFgamma;CVAP;PN-II;PN2;Amyloid beta A4;APP;Aβ42;preA4;Abeta 40;amyloid beta 40;Amyloid Beta 42;Amyloid Precursor;Amyloid Precursor Protein 695;APP695;Aβ(1-40);Aβ(1-42);Aβ40;Beta-amyloid protein 40;APP A4 AD1;A4;A4 amyloid protein;AICD-50;AICD-57;AICD-59;AID(50);AID(57);AID(59);Alzheimer disease amyloid protein;Amyloid beta (A4) precursor protein;Amyloid beta A4 protein;Amyloid beta precursor protein;Amyloid beta protein;Amyloid intracellular domain 50;Amyloid intracellular domain 57;Amyloid intracellular domain 59;Beta amyloid peptide;Beta-amyloid precursor protein;Beta-APP40;Beta-APP42;C31;Cerebral vascular amyloid peptide;Gamma-CTF(50);Gamma-CTF(57);Gamma-CTF(59);peptidase nexin II;PN 2;PN II;Protease nexin II;Protease nexin-II;S-APP-alpha;S-APP-beta;Soluble APP-beta

Research Areas:Neuroscience

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:5C9

UNIProt ID:P05067

Accession:

Background:This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind toThe acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others formThe protein basis ofThe amyloid plaques found inThe brains of patients with Alzheimer disease. In addition, two ofThe peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human Amyloid-β protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000

Calculated MW:87 kDa

ObservedMW:100 kDa