Recombinant alpha smooth muscle Actin Monoclonal Antibody

SKU: AN301435L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:alpha smooth muscle Actin

Target Synonym:AAT;GIG;MYMY;Growth inhibiting gene;AAT6;ACTSA;MYMY5;ACTA2;actin;a actin;Actin aortic smooth muscle;Growth inhibiting gene 46;ACTVS;GIG46;Actin alpha 2 smooth muscle aorta;Alpha 2 actin;Alpha actin 2;Alpha cardiac actin;alpha sma;Alpha-actin-2;aortic smooth muscle;Cell growth inhibiting gene 46 protein;Cell growth-inhibiting gene 46 protein;α-SMA;a actin;AAT6;ACTA;ACTA2;Actin aortic smooth muscle;Actin;ACTSA;ACTVS;GIG46;Growth inhibiting gene 46;MYMY5

Research Areas:Signal Transduction;Stem Cells;Cardiovascular;Developmental Biology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse

Application:WB;IHC;IF;FCM;IP

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A130

UNIProt ID:P62736

Accession:

Background:Alpha smooth muscle actin encoded by the ACTA2 gene is a key protein in the highly conserved actin family, which plays a crucial role in cell motility, structure and integrity. This isoform is predominantly expressed in vascular smooth muscle cells, where it is essential for maintaining the structure and function of blood vessels and other smooth muscle tissues. Mutations in ACTA2 are linked to various vascular disorders, including familial thoracic aortic aneurysms and dissections (TAAD) and multisystemic smooth muscle dysfunction syndrome.

Concentration:1 mg/mL

Immunogen:Recombinant human alpha smooth muscle Actin fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:2000;IHC 1:1000-1:5000;IF 1:50;FCM 1:50-1:100;IP 1:50-1:100

Calculated MW:42 kDa

ObservedMW:42 kDa