Recombinant ADA Monoclonal Antibody

SKU: AN302037L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:ADA

Target Synonym:ADA;adenosine deaminase;adenine deaminase;Adenosine Aminhydrolase;EC 3.5.4.4;ADA1;Adenosine aminohydrolase

Research Areas:Epigenetics and Nuclear Signaling;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A757

UNIProt ID:P00813

Accession:

Background:Adenosine deaminase (ADA) catalyzes adenosine degradation. Lack of this enzyme leads to the accumulation of toxic metabolites causing severe combined immunodeficiency (ADA-SCID), an autosomal recessive disorder. Differentiation and function of T cells, B cells, and natural killer cells are impaired in ADA-SCID patients leading to recurrent infections. Gene therapies for ADA-SCID were reported to correct the metabolic defect and restore the deficient immune function.

Concentration:1 mg/mL

Immunogen:Peptide. This information is proprietary to PTMab.

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:1000

Calculated MW:41 kDa

ObservedMW:41 kDa