Rat VE-Cadherin Cdh5 ELISA Kit PicoKine®

SKU: EK1916

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Rat

Applications: ELISA

Application Details:

Gene Name: Cdh5

Specificity: Natural and recombinant rat VE-Cadherin/CD144

Background: Cadherin 5, type 2 or VE-cadherin also known as CD144, is a type of cadherin. It is encoded by the human gene CDH5. This gene is mapped to 19p14. VE-cadherin is a classical cadherin from the cadherin superfamily and the gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell–cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions.

Immunogen: Expression system for standard: NS0; Immunogen sequence: D46 - Q599

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Reference:

Uniprot ID: F1M7E5

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 307618

Protein Name: Cadherin-5

Gene Full Name: cadherin 5

Synonyms: 7B4; 7B4 antigen; Cadherin 5; CD144; CDH5; FLJ17376; Vascular endothelial cadherin; VE cadherin