Rat Transcription factor HES-1,HES1 ELISA KIT

SKU: E2564Ra

Size:96 Tests-1 Kit

Background:Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity. May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage (By similarity). {ECO:0000250, ECO:0000269|PubMed:8649374}.

Research_area:

Applications:ELISA

Target_protein:Hes1

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.15ng/ml

Detection range:0.2-60ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Transcription factor HES-1

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q04666

MASS(Da):29622

GeneID:29577

Synonyms:Hes1 Hes-1 Hl

Gene names:Hes1

Standard solution:64ng/ml