Rat STC2/Stanniocalcin 2 ELISA Kit PicoKine®

SKU: EK1995

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Rat

Applications: ELISA

Application Details:

Gene Name: Stc2

Specificity: Natural and recombinant rat STC2

Background: Stanniocalcin-2 is a protein that in humans is encoded by the STC2 gene. It is mapped to 10q12. This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers. STC2 has opposite effects on calcium and phosphate homeostasis as compared to Stc1.

Immunogen: Expression system for standard: NS0; Immunogen sequence: T25-R296

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Reference:

Uniprot ID: Q9R0K8

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 63878

Protein Name: Stanniocalcin-2

Gene Full Name: stanniocalcin 2

Synonyms: stanniocalcin 2; Stanniocalcin related protein; STC 2; STC related protein; STC2; STCRP