Rat Peroxisome proliferator-activated receptor gamma,PPARG ELISA KIT

SKU: E0284Ra

Size:96 Tests-1 Kit

Background:Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses. Plays a role in the regulation of cardiovascular circadian rhythms by regulating the transcription of ARNTL/BMAL1 in the blood vessels. {ECO:0000250|UniProtKB:P37231, ECO:0000250|UniProtKB:P37238}.

Research_area:

Applications:ELISA

Target_protein:Pparg

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.01ng/ml

Detection range:0.05-20ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Peroxisome Proliferator-activated receptor γ

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O88275

MASS(Da):57567

GeneID:25664

Synonyms:Pparg Nr1c3

Gene names:Pparg

Standard solution:24ng/ml