Rat Nadphoxidase 4, NOX4 ELISA Kit

SKU: E1298Ra

Size:96 Tests-1 Kit

Background:Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.

Research_area:Cardiovascular; Signal Transduction; Metabolism; Cell Biology

Applications:ELISA

Target_protein:NOX4

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.11ng/ml

Detection range:0.2-60ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:NADPH oxidase 4

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q924V1

MASS(Da):66,469

GeneID:85431

Synonyms:Kidney oxidase-1;Kidney superoxide-producing NADPH oxidase;KOX-1;NADPH oxidase 4;NOX4

Gene names:Nox4

Standard solution:64ng/ml