Rat Glypican 1, GPC1 ELISA Kit

SKU: E1993Ra

Size:96 Tests-1 Kit

Background:Cell surface proteoglycan that bears heparan sulfate. May act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. Required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling. Binds Cu(2+) or Zn(2+) ions (By similarity). Binds, via the heparan sulfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination.

Research_area:Others

Applications:ELISA

Target_protein:GPC1

Reactivity:Rat

Assay type:Sandwich

Sensitivity:34.14ng/L

Detection range:70-15000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Glypican 1

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P35053

MASS(Da):61,734

GeneID:58920

Synonyms:Glypican-1;GPC 1;GPC1;HSPG M12;Secreted glypican-1

Gene names:GPC1

Standard solution:16000ng/L