Rat Fructose-1, 6-bisphosphatase 1, FBP1 ELISA Kit

SKU: E0977Ra

Size:96 Tests-1 Kit

Background:Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.

Research_area:Others

Applications:ELISA

Target_protein:FBP1

Reactivity:Rat

Assay type:Sandwich

Sensitivity:9.14ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Fructose-1,6-Bisphosphatase 1

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P19112

MASS(Da):39,609

GeneID:24362

Synonyms:D-fructose-1,6-bisphosphate 1-phosphohydrolase 1;FBP 1;FBP1;FBPase 1;Fructose-1,6-bisphosphatase 1;Liver FBPase

Gene names:FBP1

Standard solution:4800ng/L