Rat Eukaryotic Translation Initiation Factor 4E-binding Protein 1,EIF4EBP1 ELISA KIT

SKU: E1720Ra

Size:96 Tests-1 Kit

Background:Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation (By similarity). Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways (PubMed:7939721). {ECO:0000250|UniProtKB:Q13541, ECO:0000269|PubMed:7939721}.

Research_area:

Applications:ELISA

Target_protein:Eif4ebp1

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.09ng/ml

Detection range:0.19-12ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Eukaryotic Translation Initiation Factor 4E-binding Protein 1

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q62622

MASS(Da):12404

GeneID:116636

Synonyms:Eif4ebp1

Gene names:Eif4ebp1

Standard solution:24ng/ml