Rat Atrial Natriuretic Peptide-converting Enzyme, CORIN ELISA Kit

SKU: E0974Ra

Size:96 Tests-1 Kit

Background:Serine-type endopeptidase involved in atrial natriuretic Peptide (NPPA) processing (PubMed: 17660514). Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation (By similarity). Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus (By similarity). Also acts as a regulator of sodium reabsorption in kidney (PubMed: 20613715). May also process pro-NPPB the B-type natriuretic Peptide (By similarity).

Research_area:Cell Biology

Applications:ELISA

Target_protein:CORIN

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.022ng/mL

Detection range:0.05-20ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Atrial Natriuretic Peptide-Converting Enzyme

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q80YN4

MASS(Da):122,757

GeneID:289596

Synonyms:Atrial natriuretic Peptide-converting enzyme;Atrial natriuretic Peptide-converting enzyme, 180 kDa soluble fragment;Atrial natriuretic Peptide-converting enzyme, activated protease fragment;Atrial natriuretic Peptide-converting enzyme, N-terminal propeptide;CORIN;Pro-ANP-converting enzyme

Gene names:CORIN

Standard solution:24ng/mL