Rat Anti-Mullerian Hormone, AMH ELISA Kit

SKU: EA0083Ra

Size:96 Tests-1 Kit

Background:Anti-Müllerian hormone (AMH), also known as Müllerian-inhibiting hormone (MIH), is a glycoprotein hormone structurally related to inhibin and activin from the transforming growth factor beta superfamily, whose key roles are in growth differentiation and folliculogenesis. In humans, the gene for AMH is AMH, on chromosome 19p13.3, while the gene AMHR2 codes for its receptor on chromosome 12. AMH is activated by SOX9 in the Sertoli cells of the male fetus. Its expression inhibits the development of the female reproductive tract, or Müllerian ducts (paramesonephric ducts), in the male embryo, thereby arresting the development of fallopian tubes, uterus, and upper vagina. AMH expression is critical to sex differentiation at a specific time during fetal development, and appears to be tightly regulated by nuclear receptor SF-1, transcription GATA factors, sex-reversal gene DAX1, and follicle-stimulating hormone (FSH). Mutations in both the AMH gene and the type II AMH receptor have been shown to cause the persistence of Müllerian derivatives in males that are otherwise normally masculinized.

Research_area:Signal Transduction

Applications:ELISA

Target_protein:AMH

Reactivity:Rat

Assay type:Competitive

Sensitivity:0.024ng/mL

Detection range:0.05 - 30ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Anti-Mullerian hormone

Species:Rat

Storage:2-8ºC

Assay time:2h 30m

UniProt accession:

MASS(Da):

GeneID:

Synonyms:AMH;Anti-Muellerian hormone;MIS;Muellerian-inhibiting substance

Gene names:AMH

Standard solution:32ng/mL